Plastic and reconstructive surgery
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Plast. Reconstr. Surg. · Jun 2016
Randomized Controlled TrialEarly versus Delayed Excision and Grafting of Full-Thickness Burns in a Porcine Model: A Randomized Study.
The standard of care for full-thickness burns is tangential excision followed by skin autografting; however, the timing of excision and grafting is subject to debate. The authors compared early (2 days) versus delayed (14 days) excision and grafting in a porcine full-thickness burn model. ⋯ Both early and late excision followed by autografting reduce scarring in a full-thickness porcine burn model. However, early excision (2 days after injury) reduces scar thickness to a greater extent than later (after 14 days) excision.