Anesthesia and analgesia
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Anesthesia and analgesia · Oct 2006
Comparative StudyThe characteristics of intravenous adenosine-induced antinociception in a rabbit model of acute nociceptive pain: a comparative study with remifentanil.
Adenosine and remifentanil are potent IV analgesics with ultrashort half-lives. The antinociceptive effect of IV adenosine has not been clearly characterized. We compared the antinociceptive effects of adenosine and remifentanil in rabbits. ⋯ Remifentanil had a rapid onset and short duration of action, and probably showed signs of tolerance development, whereas the antinocieptive effect of adenosine was slow in onset and long-lasting, despite its ultrashort plasma half-life and the immediate on-off profiles of its vasodilating effect.
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Anesthesia and analgesia · Oct 2006
Editorial CommentDon't confuse the anesthetic with the anesthesiologist!
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Anesthesia and analgesia · Oct 2006
Letter Case ReportsPropofol infusion syndrome--a fatal case at a low infusion rate.