Anesthesia and analgesia
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Anesthesia and analgesia · Oct 2011
The effects of anesthetic preconditioning with sevoflurane in an experimental lung autotransplant model in pigs.
Ischemia-reperfusion lung injury is doubly important in thoracic surgery because of the associated ventilation damage to 1 lung. In this study we evaluated the cytoprotective effects of sevoflurane in a pulmonary autotransplant model in pigs. ⋯ We demonstrated that sevoflurane decreased the inflammatory response and oxidative stress in a live ischemia-reperfusion lung model.