Anesthesia and analgesia
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Anesthesia and analgesia · Mar 2011
Randomized Controlled Trial Comparative Study Clinical TrialA randomized comparison of the use of an optical compared with a rigid laryngoscope on the success rate of novices performing tracheal intubation.
Proficiency in tracheal intubation is a difficult skill to acquire, especially when using a rigid laryngoscope. We compared success in tracheal intubation by novices using an optical laryngoscope with that achieved with a rigid laryngoscope. ⋯ Intubation time was shorter using the optical laryngoscope (35 seconds; 95% confidence interval, 27-44 seconds) compared with the rigid laryngoscope (75 seconds; 95% confidence interval, 59-90 seconds) in successfully intubated patients (P < 0.001). Our study demonstrated greater successful tracheal intubation and reduced intubation time during the first two attempted intubations by novices using an optical compared with a rigid laryngoscope.
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Anesthesia and analgesia · Mar 2011
Randomized Controlled Trial Comparative Study Clinical TrialThe efficacy and safety of fentanyl buccal tablet compared with immediate-release oxycodone for the management of breakthrough pain in opioid-tolerant patients with chronic pain.
Current clinical guidelines have identified the need for studies comparing the effect of different short-acting or rapid-onset opioids for the treatment of breakthrough pain (BTP). In this study we evaluated the efficacy and safety of treatment with fentanyl buccal tablet (FBT) in comparison with immediate-release oxycodone in alleviating BTP in opioid-tolerant patients with chronic pain. ⋯ FBT resulted in more rapid onset of analgesia and was generally well tolerated in comparison with oxycodone for the treatment of BTP in opioid-tolerant patients.
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Anesthesia and analgesia · Mar 2011
Randomized Controlled Trial Multicenter Study Comparative StudyClosed-loop coadministration of propofol and remifentanil guided by bispectral index: a randomized multicenter study.
We have developed a proportional-integral-derivative controller allowing the closed-loop coadministration of propofol and remifentanil, guided by a Bispectral Index (BIS) monitor, during induction and maintenance of general anesthesia. The controller was compared with manual target-controlled infusion. ⋯ The controller allows the automated delivery of propofol and remifentanil and maintains BIS values in predetermined boundaries during general anesthesia better than manual administration.
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Anesthesia and analgesia · Mar 2011
Randomized Controlled Trial Comparative StudyA comparison of sartorius versus quadriceps stimulation for femoral nerve block: a prospective randomized double-blind controlled trial.
Femoral nerve block is widely used for regional anesthesia and analgesia in many lower limb operations. Peripheral nerve stimulation of the femoral nerve may elicit 1 of 2 responses: contraction of the sartorius muscle through stimulation of its muscular branch or contraction of the quadriceps muscle through stimulation of its respective muscular branches. Historically, a quadriceps response has been preferred. We hypothesized that the success of femoral nerve block using a sartorius muscle evoked motor response is equivalent to that using quadriceps muscle twitch response. This prospective randomized double-blind controlled trial compared sartorius or quadriceps muscle evoked motor response as the end point for stimulation for femoral nerve block. ⋯ Our study demonstrated that using sartorius or quadriceps evoked muscle twitch as an end point of stimulation was associated with an equivalent degree of femoral nerve block.
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Anesthesia and analgesia · Mar 2011
Randomized Controlled Trial Comparative StudyA comparison of the classic and a modified laryngeal mask airway (OPLAC™) in adult patients.
A modified disposable laryngeal mask airway (LMA) (Oro-Pharyngo-Laryngeal Airway Cap, OPLAC™) was developed in our department. In this study, we compared the performance of the LMA Classic™ with that of the OPLAC. ⋯ Both devices have comparable airflow resistance and are easy to insert. The OPLAC requires less insertion time, has less variation on insertion time, fits better into the laryngopharynx, is less likely to cause gastric insufflations, and has a higher sealing pressure.