Anesthesia and analgesia
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Anesthesia and analgesia · Mar 2012
Meta Analysis Comparative StudyPerioperative fluid management strategies in major surgery: a stratified meta-analysis.
Both "liberal" and "goal-directed" (GD) therapy use a large amount of perioperative fluid, but they appear to have very different effects on perioperative outcomes. We sought to determine whether one fluid management strategy was superior to the others. ⋯ Perioperative outcomes favored a GD therapy rather than liberal fluid therapy without hemodynamic goals. Whether GD therapy is superior to a restrictive fluid strategy remains uncertain.