Anesthesia and analgesia
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Anesthesia and analgesia · Feb 2013
Randomized Controlled TrialValidation of a mathematical model for ultrasound assessment of gastric volume by gastroscopic examination.
Pulmonary aspiration of gastric contents is a serious perioperative complication. Previous models of ultrasound gastric volume assessment are preliminary and have not been validated by an external "gold standard." In the present study we propose a more accurate model based on prospective data obtained from 108 patients undergoing bedside gastric sonography and upper gastrointestinal endoscopy (UGE). ⋯ We report a new prediction model to assess gastric fluid volume using standard 2-dimentional bedside ultrasound that has several advantages over previously reported models.
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Anesthesia and analgesia · Feb 2013
Randomized Controlled Trial Multicenter StudyA multicenter, randomized, controlled study evaluating preventive etanercept on postoperative pain after inguinal hernia repair.
Chronic postsurgical pain (CPSP) affects between 5% and 70% of surgical patients, depending on the surgery. There is no reliable treatment for CPSP, which has led to an increased emphasis on prevention. In this study, we sought to determine whether preventive etanercept can decrease the magnitude of postoperative pain and reduce the incidence of CPSP. ⋯ Although preventive etanercept was superior to saline in reducing postoperative pain on some measures, the effect sizes were small, transient, and not statistically significant. Different dosing regimens in a larger population should be explored in future studies.