Anesthesia and analgesia
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Anesthesia and analgesia · Nov 2015
Randomized Controlled TrialNitrous Oxide for the Treatment of Chronic Low Back Pain.
Neuropathic back pain is mediated, at least partially, by N-methyl-D-aspartate (NMDA) receptors. Nitrous oxide (N2O) is an NMDA receptor antagonist. We therefore tested the primary hypothesis that patients receiving N2O have lower pain scores after epidural steroid injection than patients not receiving N2O. ⋯ N2O administration did not improve pain or psychological or physical aspects of health-related quality of life. N2O does not appear to be an effective treatment for chronic neuropathic back pain.
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Anesthesia and analgesia · Nov 2015
The Impact of Incident Postoperative Delirium on Survival of Elderly Patients After Surgery for Hip Fracture Repair.
The impact of delirium on survival of elderly patients remains undetermined with conflicting results from clinical studies and meta-analysis. In this study, we assessed the relationship between long-term mortality and incident postoperative delirium in elderly patients undergoing hip fracture repair. ⋯ Incident postoperative delirium was not significantly associated with decreased survival in elderly patients undergoing hip fracture repair.