Anesthesia and analgesia
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Anesthesia and analgesia · Nov 2016
Comparative StudyThe Effect of Lipid Emulsion on Pharmacokinetics of Bupivacaine in Rats: Long-Chain Triglyceride Versus Long- and Medium-Chain Triglyceride.
Lipid infusions have been proposed to treat local anesthetic-induced cardiac toxicity. This study compared the effects of long-chain triglyceride (LCT) emulsions with those of long- and medium-chain triglyceride (LCT/MCT) emulsions on the pharmacokinetics of bupivacaine in a rat model. ⋯ LCT emulsions are more effective than LCT/MCT emulsions in the metabolism of bupivacaine through demonstration of a superior pharmacokinetic profile.
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Anesthesia and analgesia · Nov 2016
US National Anesthesia Workload on Saturday and Sunday Mornings.
In order to provide guidance to organizations considering elective weekend surgical case scheduling, we analyzed data from the American Society of Anesthesiologist's Anesthesia Quality Institute. We determined the US anesthesia workload on Saturdays and Sundays. ⋯ The imputed Saturday elective schedule represents a tiny percentage of overall anesthetic workload nationwide. Saturday elective surgery is currently an uncommon practice in the United States. Based on this prior knowledge, organizations considering changes to their current scheduling strategies should perform a thorough statistical analysis of their local workload prior to implementation and apply evidence-based criteria to guide their decision-making process.