Anesthesia and analgesia
-
Anesthesia and analgesia · Nov 2016
Meta AnalysisThe Effect of Preoperative Pregabalin on Postoperative Nausea and Vomiting: A Meta-Analysis.
Nonopioid adjuvant medications are increasingly included among perioperative Enhanced Recovery After Surgery protocols. Preoperative pregabalin has been shown to improve postoperative pain and limit reliance on opioid analgesia. Our group investigated the ability of preoperative pregabalin to also prevent postoperative nausea and vomiting (PONV). ⋯ Preoperative pregabalin is associated with significant reduction of PONV and should not only be considered as part of a multimodal approach to postoperative analgesia but also for prevention of PONV.