Anesthesia and analgesia
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Anesthesia and analgesia · Aug 2020
Randomized Controlled TrialA Prospective, Randomized, Double-Blinded Study of the Effect of Intravenous Ondansetron on the Effective Dose in 50% of Subjects of Prophylactic Phenylephrine Infusions for Preventing Spinal Anesthesia-Induced Hypotension During Cesarean Delivery.
Pre-spinal-anaesthesia administration of IV ondansetron 4 mg reduces the ED50 of prophylactic phenylephrine infusion by 26% among patients undergoing elective Caesarean section.
pearl -
Anesthesia and analgesia · Aug 2020
Comparative Study Observational StudyAnesthesia With and Without Nitrous Oxide and Long-term Cognitive Trajectories in Older Adults.
Although exposure to surgery/anesthesia is associated with a small cognitive decline among the elderly, there is no impact from the presence or absence of nitrous oxide.
pearl -
Anesthesia and analgesia · Aug 2020
Randomized Controlled TrialEffect of Different Concentrations of Propofol Used as a Sole Anesthetic on Pupillary Diameter: A Randomized Trial.
Propofol has a dose-dependent effect on pupillary diameter, which is positively correlated with BIS.
pearl -
Anesthesia and analgesia · Aug 2020
Observational StudyRatios of Plasma and Platelets to Red Blood Cells in Surgical Patients With Acute Intraoperative Hemorrhage.
The relationships between the ratios of transfused allogeneic blood products and clinical outcomes in patients with acute intraoperative hemorrhage are poorly defined. ⋯ Transfusion ratios in surgical patients with critical intraoperative hemorrhage were largely related to surgical and hemostatic features rather than baseline patient characteristics. Higher ratios were not associated with improved outcomes.
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Anesthesia and analgesia · Aug 2020
Routine Intraoperative Inhaled Milrinone and Iloprost Reduces Inotrope Use in Patients Undergoing Cardiac Surgery: A Retrospective Cohort Pilot Study.
Catecholamine inotropes are frequently used after cardiopulmonary bypass (CPB) but may have undesirable effects. The aim was to identify whether the routine use of inhaled pulmonary vasodilators might reduce the requirement for inotrope drugs after cardiac surgery. ⋯ Routine use of inhaled milrinone 4 mg and iloprost 20 µg before and after CPB is associated with reduced postoperative inotrope use.