Wiener klinische Wochenschrift
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Wien. Klin. Wochenschr. · Feb 2025
Review Meta AnalysisChildhood asthma and mould in homes-A meta-analysis.
Asthma is a multifaceted and multicausal disease. Childhood asthma is strongly influenced by genetic traits and is characterized by hyperreactivity of the airways so that also unspecific triggers including moulds can trigger an asthma attack. Therefore, it is undisputed that moulds in the home can cause asthma attacks in asthmatic children. ⋯ The cohort studies also showed no publication bias but substantial heterogeneity (I2 = 60.5, p = 0.005). Heterogeneity could be partly explained by percentage of male children, age of participants, and publication year, but was not affected by study quality. In conclusion, living in mouldy homes during childhood seems to increase the risk of later developing bronchial asthma.
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Wien. Klin. Wochenschr. · Feb 2025
Observational StudyMaternal and neonatal outcomes in kidney transplant recipients: a single-center observational study.
Pregnancy poses a high risk for adverse maternal and neonatal outcomes in kidney transplant recipients (KTRs), and data on long-term allograft functions compared to the healthy population are still limited. Therefore, we aimed to conduct a comparative analysis of maternal and neonatal outcomes in KTRs. ⋯ The KTRs exhibit comparable neonatal mortality and NICU admission rates but have higher rates of preeclampsia and preterm birth. Importantly, graft functions worsen significantly during postpartum follow-up.
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Wien. Klin. Wochenschr. · Feb 2025
Attitudes of the general population and mental health practitioners towards blended therapy in Austria.
Mental health problems are steadily increasing worldwide. In Austria, the overall supply of mental health services is low, especially in rural areas. Mobile technology and a blended care approach have the potential to overcome problems with service provision. The aim of this study was to map the attitudes of practitioners and people living in Austria towards blended therapy. ⋯ Practitioners' attitudes are important for implementation of blended therapy. More awareness might help against the cautiousness as well as implementing digital health applications in Austrian health policies.
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Wien. Klin. Wochenschr. · Feb 2025
Deciphering the role of lactate as a prognostic indicator in pediatric diabetic ketoacidosis.
Serum lactate levels have been recognized as a robust marker for predicting disease severity and survival in many critically ill children but consensus is lacking regarding its utility in diabetic ketoacidosis. This study aimed to investigate the relationship between initial lactate levels and disease severity in pediatric patients presenting with diabetic ketoacidosis. ⋯ Although there is an association between the severity of acidosis and lactate levels in diabetic ketoacidosis, contrary to expectations, this relationship was not found to be associated with adverse outcomes. An important point not to be overlooked by pediatricians is that elevated lactate levels in diabetic ketoacidosis may not always herald poor outcomes.
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General practice/family medicine has recently been recognized as a medical discipline in Austria. This paper is a short report on the prevailing understanding of its goals and subjects, comparing the Austrian perception with international definitions. It comments on shortcomings and introduces an outline for the development of a revised professional theory. ⋯ Now it is the fragmentation that extensive specialization entails that gives a new meaning to generalist, contextual and patient-centered medicine. This change needs to be analyzed and understood. A description of the responsibilities, tasks and very specific methods unique to the discipline will be developed, which should enable the sensible, contemporary use of general practice/family medicine for the benefit of patients and the healthcare system.