Wiener klinische Wochenschrift
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Wien. Klin. Wochenschr. · Feb 2025
Conservative treatment of knee arthrofibrosis according to a cellular cytokine-based model : A retrospective pilot evaluation.
Arthrofibrosis (AF) is a relatively frequent complication after knee surgery, leading to painful limitation of joint mobility. Currently, intense stretching is performed in many patients, without improvements in mobility. A novel concept, established on a cellular, cytokine-based model, advocates to consider the warning function of pain and to terminate forced joint mobilization to disrupt the cycle of arthrofibrosis. Based on these findings, our clinic developed a comprehensive antifibrotic treatment protocol. The aim of this analysis was to evaluate the patients treated so far. ⋯ Based on this pilot evaluation, the comprehensive conservative AF program seems to have high potential. Therefore, larger future studies should be conducted to validate this concept.
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Wien. Klin. Wochenschr. · Feb 2025
A rare case of a rectal neuroendocrine neoplasm growing within a lipoma with ulcerative lesions.
Neuroendocrine neoplasms (NENs) are a heterogeneous group of tumors with different immunophenotypes, morphological features, clinical presentations, and outcomes. Therefore, the diversity of NENs can easily confuse clinicians and lead to misdiagnosis. ⋯ Through the review of this case and relevant literature, we further analyze the growth pattern of NENs and lipomas. Additionally, we hope to enhance clinicians' awareness of a NEN that grew insidiously within a lipoma with surface ulcerative lesions, to make accurate diagnoses and treatments in time.
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Wien. Klin. Wochenschr. · Feb 2025
Attitudes of the general population and mental health practitioners towards blended therapy in Austria.
Mental health problems are steadily increasing worldwide. In Austria, the overall supply of mental health services is low, especially in rural areas. Mobile technology and a blended care approach have the potential to overcome problems with service provision. The aim of this study was to map the attitudes of practitioners and people living in Austria towards blended therapy. ⋯ Practitioners' attitudes are important for implementation of blended therapy. More awareness might help against the cautiousness as well as implementing digital health applications in Austrian health policies.
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Colchicine is an anti-inflammatory herbal medicine with a history stretching back thousands of years. It is a cornerstone in the acute and prophylactic treatment of gout and has secured a permanent place in the standard pharmacological repertoire for familial Mediterranean fever, pericarditis, neutrophilic dermatoses, Behçet's disease and severe aphthous ulcers refractory to oral treatment. ⋯ Clinical studies in recent years also demonstrated an effect for acute coronary syndrome and atrial fibrillation. This review article highlights the efficacy and safety profile of colchicine and provides insights into recent and potential future evidence-based fields of application.