Epilepsia
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Randomized Controlled Trial Comparative Study Clinical Trial
Dose-dependent safety and efficacy of zonisamide: a randomized, double-blind, placebo-controlled study in patients with refractory partial seizures.
To evaluate the safety and efficacy of zonisamide (ZNS) as adjunctive treatment in patients with refractory localization-related epilepsy. ⋯ ZNS provides dose-dependent, effective, and generally well-tolerated adjunctive therapy in patients with partial seizures.