International journal of dermatology

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• Int. J. Dermatol. · Apr 2015

  Meta Analysis

  Association of HLA-B*1502 allele with lamotrigine-induced Stevens-Johnson syndrome and toxic epidermal necrolysis in Han Chinese subjects: a meta-analysis.

  Despite several studies investigating the association between the human leukocyte antigen HLA-B*1502 allele and lamotrigine-induced Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) in Han Chinese subjects, the relationship remains unclear. ⋯ We found a statistical association between HLA-B*1502 and lamotrigine-induced SJS/TEN in Han Chinese subjects. Future studies with larger sample sizes are suggested to verify the results.

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