Indian pediatrics
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Randomized Controlled Trial Clinical Trial
Vitamin a status of pregnant women and effect of post partum vitamin a supplementation.
To assess the Vitamin A status of pregnant women in their third trimester using maternal serum retinol levels as the indicator; and (ii) To assess the impact of postpartum Vitamin A supplementation on the Vitamin A status of exclusively breastfed infants. ⋯ There is a high prevalence of inapparent Vitamin A deficiency (29.7%) in pregnant women in their third trimester from lower socio-economic strata. Postpartum Vitamin A supplementation had a beneficial impact on the infant serum retional and the breast milk retinol level but no effect on infant growth.
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Randomized Controlled Trial Clinical Trial
Effectiveness and cost-effectiveness of albendazole in improving nutritional status of pre-school children in urban slums.
To study the clinical efficacy and the incremental cost-effectiveness of albendazole in improving the nutritional status of pre-school children. ⋯ Six monthly albendazole reduces the risk of stunting with a small increase in the expenditure on health care from the payer's perspective. Larger trials are needed to study the effect of albendazole on prevention of stunting, cognitive functions and all-cause childhood mortality.
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Randomized Controlled Trial Multicenter Study Clinical Trial
Multicenter randomized placebo controlled trial of therapy with intravenous immunoglobulin in decreasing mortality due to neonatal sepsis.
To determine whether therapy with intravenous immunoglobulin G (IVIG) would decrease mortality in neonatal sepsis. ⋯ In the sample studied therapy with IVIG did not reduce mortality in neonatal sepsis
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Randomized Controlled Trial Comparative Study Clinical Trial
Double blind randomized comparative evaluation of nimesulide and paracetamol as antipyretics.
To compare the efficacy and safety of nimesulide and paracetamol as antipyretic agents. ⋯ Nimesulide is more effective than paracetamol as an antipyretic agent and is safe for use in infants and children.
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Randomized Controlled Trial Clinical Trial
Prophylactic metoclopramide administered immediately after the induction of anesthesia has no effect on the incidence of postoperative emesis after strabismus surgery.
To evaluate the efficacy of metoclopramide (0.25 mg/kg) administered IV immediately after induction of general anesthesia for the prevention of postoperative emesis in children undergoing, elective strabismus surgery. ⋯ Metoclopramide in a dose of 0.25 mg/kg administered intravenously prior to manipulation of eyeball is devoid of the effects but is not effective in preventing postoperative emesis in children undergoing strabismus surgery.