Headache
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Randomized Controlled Trial Comparative Study Clinical Trial
Treatment of chronic cervical-associated headache with botulinum toxin A: a pilot study.
To see whether therapy with botulinum toxin A may prove to be an effective treatment for headache of musculoskeletal origin. ⋯ Fourteen subjects who received botulinum toxin A and 12 who received saline completed the study. At both 2 and 4 weeks post injection, the treatment group showed a significant improvement in pain and range of motion from preinjection levels (P<.01). The placebo group demonstrated no statistically significant changes at any posttreatment time.