Journal of neurology, neurosurgery, and psychiatry
-
J. Neurol. Neurosurg. Psychiatr. · May 2014
Trends in the incidence of ischaemic stroke in young adults between 1985 and 2011: the Dijon Stroke Registry.
Recent data have suggested that stroke incidence in young people may be rising. In this population-based study, we aimed to determine whether the incidence of stroke in people aged <55 years old had changed over the last three decades. ⋯ Multiple factors may account for the increased incidence of ischaemic stroke in people aged <55 years including changes in vascular risk factors, better awareness of the disease and treatment options in the population and among practitioners leading to more frequent referrals for specialised care, and improvements in stroke diagnosis. Stroke prevention must be encouraged even in young adults.
-
J. Neurol. Neurosurg. Psychiatr. · May 2014
The safety and efficacy of thalamic deep brain stimulation in essential tremor: 10 years and beyond.
Deep brain stimulation (DBS) has proven to be a safe and effective therapy for refractory essential tremor, but information regarding long-term outcomes is lacking. ⋯ Thalamic DBS is a safe and effective therapy in patients with essential tremor followed for up to 13 years.
-
J. Neurol. Neurosurg. Psychiatr. · May 2014
Cognitive deficits in mild Parkinson's disease are associated with distinct areas of grey matter atrophy.
The neuroanatomical substrates underlying cognitive impairment in Parkinson's disease (PD) remain poorly understood. To address this gap, we compared the grey matter atrophy patterns in PD patients with mild cognitive impairment (PD-MCI) with PD patients having no cognitive impairment (PD-NCI), and examined relationships between atrophic regions and cognitive performance in specific domains. ⋯ Domain specific cognitive impairment in mild PD is associated with distinct areas of grey matter atrophy. These regions of atrophy are demonstrable early in the disease course and may serve as a biomarker for dementia in PD.
-
J. Neurol. Neurosurg. Psychiatr. · May 2014
Case ReportsThe clinical features of psychogenic movement disorders resembling tics.
Psychogenic movement disorders (PMDs) may be difficult to differentiate from organic abnormal movements. ⋯ Movements resembling tics are observed in a small proportion of patients with PMDs. Clinical features can help to differentiate them from organic tics.