European journal of clinical investigation
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Eur. J. Clin. Invest. · Nov 2020
Randomized Controlled TrialNon-specific analgesia during a clinical trial in fibromyalgia.
When patients suffering from fibromyalgia undergo a therapeutic trial, a non-negligible part of analgesia is not explained by the drug itself. The mechanisms of this non-specific effect need to be understood. ⋯ The changes observed concomitantly to non-specific pain analgesia might be related to mild changes in brain functioning, based on convergent literature data.