European journal of clinical investigation
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Eur. J. Clin. Invest. · Jan 2023
Prehospital respiratory early warning score for airway management in-ambulance: a score comparison.
Prehospital Respiratory Early Warning Scores to estimate the requirement for advanced respiratory support is needed. To develop a prehospital Respiratory Early Warning Score to estimate the requirement for advanced respiratory support. ⋯ Our results showed that REWS is a remarkably aid for the decision-making process in the management of advanced respiratory support in prehospital care. Including this score in the prehospital scenario could improve patients' care and optimise the resources' management.
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Eur. J. Clin. Invest. · Jan 2023
The role of antiplatelet therapies on incidence and mortality of hepatocellular carcinoma.
To evaluate the impact of antiplatelet therapy (APT)on the incidence of hepatocellular carcinoma (HCC) and mortality following its treatment. ⋯ Current data suggest that APT correlated with higher HCC incidence and poor overall survival following tumour treatment.
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Eur. J. Clin. Invest. · Jan 2023
Review Meta AnalysisAngiotensin Converting Enzyme 2 level and its significance in COVID19 and other diseases patients.
Angiotensin-converting enzyme 2 (ACE2) expressions and its modulation are of great interest as being a key receptor for severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) and the protective arm of the rennin-angiotensin axis, maintaining cardiovascular homeostasis. However, ACE2 expressions and their modulation in the healthy and disease background are yet to be explored. ⋯ It was observed that utilizing the ACE2 by SARS-CoV2 for its entry and its consequence leads to several complications. So there is a need to investigate the underlying mechanism along with novel therapeutic strategies.
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Eur. J. Clin. Invest. · Jan 2023
Meta AnalysisA systematic review and meta-analysis on oncological radiotherapy in patients with a cardiac implantable electronic device: prevalence and predictors of device malfunction in 3121 patients.
The number of patients with cardiac implantable electronic devices (CIEDs) undergoing radiotherapy (RT) for cancer treatment is growing. At present, prevalence and predictors of RT-induced CIEDs malfunctions are not defined. ⋯ Radiotherapy related CIEDs malfunction had a prevalence ranging from 4% to 20%. The use of neutron-producing energies and more complex devices (ICD/CRT-D) were associated with higher risk of device malfunction, while the radiation dose at CIED did not significantly impact on the risk unless higher doses (>10 Gy) were used.