Lancet
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Low-dose aspirin is of definite and substantial net benefit for many people who already have occlusive vascular disease. We have assessed the benefits and risks in primary prevention. ⋯ UK Medical Research Council, British Heart Foundation, Cancer Research UK, and the European Community Biomed Programme.
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Randomized Controlled Trial Multicenter Study
Early physical and occupational therapy in mechanically ventilated, critically ill patients: a randomised controlled trial.
Long-term complications of critical illness include intensive care unit (ICU)-acquired weakness and neuropsychiatric disease. Immobilisation secondary to sedation might potentiate these problems. We assessed the efficacy of combining daily interruption of sedation with physical and occupational therapy on functional outcomes in patients receiving mechanical ventilation in intensive care. ⋯ None.