Lancet
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Meta Analysis
Efficacy of β blockers in patients with heart failure plus atrial fibrillation: an individual-patient data meta-analysis.
Atrial fibrillation and heart failure often coexist, causing substantial cardiovascular morbidity and mortality. β blockers are indicated in patients with symptomatic heart failure with reduced ejection fraction; however, the efficacy of these drugs in patients with concomitant atrial fibrillation is uncertain. We therefore meta-analysed individual-patient data to assess the efficacy of β blockers in patients with heart failure and sinus rhythm compared with atrial fibrillation. ⋯ Menarini Farmaceutica Internazionale (administrative support grant).