Lancet
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Meta Analysis Comparative Study
Comparative efficacy and tolerability of antidepressants for major depressive disorder in children and adolescents: a network meta-analysis.
Major depressive disorder is one of the most common mental disorders in children and adolescents. However, whether to use pharmacological interventions in this population and which drug should be preferred are still matters of controversy. Consequently, we aimed to compare and rank antidepressants and placebo for major depressive disorder in young people. ⋯ National Basic Research Program of China (973 Program).
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Multicenter Study Meta Analysis
Body-mass index and all-cause mortality: individual-participant-data meta-analysis of 239 prospective studies in four continents.
Overweight and obesity are increasing worldwide. To help assess their relevance to mortality in different populations we conducted individual-participant data meta-analyses of prospective studies of body-mass index (BMI), limiting confounding and reverse causality by restricting analyses to never-smokers and excluding pre-existing disease and the first 5 years of follow-up. ⋯ UK Medical Research Council, British Heart Foundation, National Institute for Health Research, US National Institutes of Health.