Lancet
-
Randomized Controlled Trial Multicenter Study
Efficiency and safety of varying the frequency of whole blood donation (INTERVAL): a randomised trial of 45 000 donors.
Limits on the frequency of whole blood donation exist primarily to safeguard donor health. However, there is substantial variation across blood services in the maximum frequency of donations allowed. We compared standard practice in the UK with shorter inter-donation intervals used in other countries. ⋯ NHS Blood and Transplant, National Institute for Health Research, UK Medical Research Council, and British Heart Foundation.
-
Randomized Controlled Trial Multicenter Study Comparative Study
The price of blood is measured in iron.
-
Retraction Of Publication
Retraction and republication-Misoprostol drug to be withdrawn from French market.
-
Randomized Controlled Trial Multicenter Study
Continuous glucose monitoring in pregnant women with type 1 diabetes (CONCEPTT): a multicentre international randomised controlled trial.
Pregnant women with type 1 diabetes are a high-risk population who are recommended to strive for optimal glucose control, but neonatal outcomes attributed to maternal hyperglycaemia remain suboptimal. Our aim was to examine the effectiveness of continuous glucose monitoring (CGM) on maternal glucose control and obstetric and neonatal health outcomes. ⋯ Juvenile Diabetes Research Foundation, Canadian Clinical Trials Network, and National Institute for Health Research.
-
Oesophageal cancer is a clinically challenging disease that requires a multidisciplinary approach. Extensive treatment might be associated with a considerable decline in health-related quality of life and yet still a poor prognosis. In recent decades, prognosis has gradually improved in many countries. ⋯ Surgery has become more standardised and centralised. Several therapeutic alternatives are available for palliative treatment. This Seminar aims to provide insights into the current clinical management, ongoing controversies, and future needs in oesophageal cancer.