JAMA : the journal of the American Medical Association
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Randomized Controlled Trial Clinical Trial
Medical decision making in situations that offer multiple alternatives.
To determine whether situations involving multiple options can paradoxically influence people to choose an option that would have been declined if fewer options were available. ⋯ The introduction of additional options can increase decision difficulty and, hence, the tendency to choose a distinctive option or maintain the status quo. Awareness of this cognitive bias may lead to improved decision making in complex medical situations.
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Randomized Controlled Trial Comparative Study Clinical Trial
Randomized comparative trial and cost analysis of 3-day antimicrobial regimens for treatment of acute cystitis in women.
To determine the efficacy, safety, and costs associated with four different 3-day regimens for the treatment of acute uncomplicated cystitis in women. ⋯ A 3-day regimen of trimethoprim-sulfamethoxazole is more effective and less expensive than 3-day regimens of nitrofurantoin, cefadroxil, or amoxicillin for treatment of uncomplicated cystitis in women. The increased efficacy of trimethoprim-sulfamethoxazole is likely related to its antimicrobial effects against E coli in the rectum, urethra, and vagina.