JAMA : the journal of the American Medical Association
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Randomized Controlled Trial Multicenter Study Clinical Trial
Maintenance phase efficacy of sertraline for chronic depression: a randomized controlled trial.
The chronic form of major depression is associated with a high rate of prevalence and disability, but no controlled research has examined the impact of long-term treatment on the course and burden of illness. ⋯ Maintenance therapy with sertraline is well tolerated and has significant efficacy in preventing recurrence or reemergence of depression in chronically depressed patients.
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Trust is the cornerstone of the patient-physician relationship. Payment methods that place physicians at financial risk have raised concerns about patients' trust in physicians to act in patients' best interests. ⋯ Most patients trusted their physicians, but FFS indemnity patients have higher levels of trust than salary, capitated, or FFS managed care patients. Patients' reports of physician behavior accounted for part of the variation in patients' trust in physicians who are paid differently. The impact of payment methods on patient trust may be mediated partly by physician behavior.
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Randomized Controlled Trial Multicenter Study Clinical Trial
Treatment of irritable bowel syndrome with Chinese herbal medicine: a randomized controlled trial.
Irritable bowel syndrome (IBS) is a common functional bowel disorder for which there is no reliable medical treatment. ⋯ Chinese herbal formulations appear to offer improvement in symptoms for some patients with IBS.