JAMA : the journal of the American Medical Association
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Randomized Controlled Trial Clinical Trial
Noninvasive positive-pressure ventilation for postextubation respiratory distress: a randomized controlled trial.
Noninvasive positive-pressure ventilation (NPPV) has been demonstrated to be effective in preventing the need for endotracheal intubation in some patients who present with acute respiratory failure. It is also used for patients who develop acute respiratory distress after extubation, but there are no randomized controlled trials that address its effectiveness in this population. ⋯ The addition of NPPV to standard medical therapy does not improve outcome in heterogeneous groups of patients who develop respiratory distress during the first 48 hours after extubation.