JAMA : the journal of the American Medical Association
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Randomized Controlled Trial Multicenter Study Comparative Study
Initial trophic vs full enteral feeding in patients with acute lung injury: the EDEN randomized trial.
The amount of enteral nutrition patients with acute lung injury need is unknown. ⋯ In patients with acute lung injury, compared with full enteral feeding, a strategy of initial trophic enteral feeding for up to 6 days did not improve ventilator-free days, 60-day mortality, or infectious complications but was associated with less gastrointestinal intolerance.
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Among adult patients with liver disease, the ability to identify those most likely to have cirrhosis noninvasively is challenging. ⋯ For identifying cirrhosis, the presence of a variety of clinical findings or abnormalities in a combination of simple laboratory tests that reflect the underlying pathophysiology increase its likelihood. To exclude cirrhosis, combinations of normal laboratory findings are most useful.
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Editorial Comment
Prevention of pneumococcal infection with vaccines: an evolving story.