Infection and immunity
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Infection and immunity · Jan 1976
Effect of penicillin on the succession, attachment, and morphology of segmented, filamentous microbes in the murine small bowel.
Indigenous segmented filamentous microbes attach to murine ileal epithelial cells. These microbes can be seen on the epithelial surface with a scanning electron microscope. They colonize preferentially the distal ileum in mice. ⋯ Vacated and partially vacated attachment sites are observed. Almost all of the organisms disappear from murine ilea after the animals are exposed to penicillin for 10 h. These observations are discussed in relation to the microbe itself and in its interaction with ileal epithelial cells.