Clinical neurology and neurosurgery
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Clin Neurol Neurosurg · Nov 2011
Randomized Controlled TrialEarly prognostic factors related to progression and malignant transformation of low-grade gliomas.
Low-grade gliomas (LGGs) are infiltrative tumors characterized by slow growth. However, during early period, LGGs can progress and transform into a malignant pathology. We analyzed the prognostic factors for progression and malignant transformation in LGGs. ⋯ In LGGs, extent of removal associated with tumor progression. The pathology of astrocytoma, especially gemistocytic astrocytoma, was an independent prognostic factor for recurrence and malignant transformation.