Clinical neurology and neurosurgery
-
Clin Neurol Neurosurg · Oct 2014
Review Meta AnalysisEffects of dexmedetomidine on outcomes following craniocerebral operation - a meta-analysis.
To evaluate the effect of dexmedetomidine on outcomes following craniocerebral operation and provide evidence for individualized medication. ⋯ Dexmedetomidine can reduce the hemodynamic response and play a role in brain protection.
-
Clin Neurol Neurosurg · Oct 2014
Review Case ReportsA review of cavernous malformations with trigeminal neuralgia.
Cavernous malformation with trigeminal neuralgia is relatively rare; only 10 cases have been reported. In deciding treatment strategies, it is helpful to classify cavernous malformation according to its origin, as follows: in the Gasserian ganglion (Type G); between the cisternal and intra-axial portions of the trigeminal nerve root (Type C); in the intra-axial trigeminal nerve root in the pons (Type P); or in the spinal tract of the trigeminal nerve root (Type S). A 62-year-old male presented with left trigeminal neuralgia (V2 area) and left facial hypoesthesia. ⋯ Histological examination confirmed a cavernous malformation. In this case, the cavernous malformation was Type C. We review cases of cavernous malformation with trigeminal neuralgia and discuss therapeutic strategies according to the area of origin.
-
Clin Neurol Neurosurg · Oct 2014
Management and outcomes of malignant posterior reversible encephalopathy syndrome.
Recognition of severe forms of posterior reversible encephalopathy syndrome (PRES) has improved. Management of these patients remains challenging, particularly in patients with the combination of edema and hemorrhage. ⋯ In contrast to historical reports of high mortality rates (16-29%) for severe and hemorrhagic PRES variants, we had no fatalities and observed favorable functional outcomes with intracranial pressure monitoring and craniectomy for malignant PRES cases who fail medical ICP management.
-
Clin Neurol Neurosurg · Oct 2014
Validation assessment of risk tools to predict outcome after thrombolytic therapy for acute ischemic stroke.
We evaluated the reliability of eight clinical prediction models for symptomatic intracerebral hemorrhage (sICH) and long-term functional outcome in stroke patients treated with thrombolytics according to clinical practice. ⋯ All eight clinical models for outcome prediction after thrombolysis for acute ischemic stroke showed fair predictive value in patients treated according daily practice. The s-TPI had the best discriminatory ability and was well calibrated in our study population.
-
Clin Neurol Neurosurg · Oct 2014
Clinical features and surgical outcomes of sporadic cerebellar hemangioblastomas.
Sporadic hemangioblastomas show a strong preference for the cerebellum. We clarify the clinical characteristics and role of surgery in sporadic cerebellar hemangioblastomas. ⋯ Sporadic cerebellar hemangioblastomas are usually associated with cysts and are voluminous by the time of diagnosis. Because these tumors result in the mass effect of posterior fossa, surgical removal is preferable and safe, and can be a timely curative strategy to prevent neurological decline.