Clinical neurology and neurosurgery
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Refractory pain syndromes often have far reaching effects and are quite a challenge for primary care providers and specialists alike to treat. With the help of site-specific neuromodulation and appropriate patient selection these difficult to treat pain syndromes may be managed. In this article, we focus on supraspinal stimulation (SSS) for treatment of intractable pain and discuss off-label uses of deep brain stimulation (DBS) and motor cortex stimulation (MCS) in context to emerging indications in neuromodulation. ⋯ Overall, a review of the literature demonstrates that DBS should be considered for refractory conditions including nociceptive/neuropathic pain, phantom limb pain, and chronic cluster headache (CCH). MCS should be considered primarily for trigeminal neuropathic pain (TNP) and central pain. DBS outcome studies for post-stroke pain as well as MCS studies for complex regional pain syndrome (CRPS) show more modest results and are also discussed in detail.
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Clin Neurol Neurosurg · Jul 2014
ReviewA review of modifying factors affecting usage of diagnostic rating scales in concussion management.
Sport-related concussion has gained increasing recognition as a result of recent legislation, public health initiatives and media coverage. Moreover, there have been substantial paradigm shifts in the management of concussion. This article will discuss the variables that affect the use of diagnostic rating scales such as ImPACT and SCAT in the current management of concussed individuals. Specifically, patient-specific modifying factors affecting test interpretation, including age, gender, fitness level, psychiatric conditions, learning disorders and other components of medical history will be addressed, as well as methodological concerns with baseline testing.
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Clin Neurol Neurosurg · Jun 2014
Review Case ReportsEndoscopic-assisted microsurgical techniques at the craniovertebral junction: 4 illustrative cases and literature review.
Endoscopic-assisted microsurgery (EAM) techniques are employed to improve visualization of the surgical field while minimizing brain retraction and trauma to neurovascular structures. There have been several reports in the literature on the indications and advantages of endoscopic-assisted techniques when operating at the craniovertebral junction (CVJ). The purpose of this study was to present illustrative cases and to perform a literature review of endoscopic-assisted microsurgical techniques at the CVJ. ⋯ EAM techniques can improve illumination and visualization of the surgical field at the CVJ. In addition, the EAM techniques can help to minimize the need for brain retraction or extensive exposures. Utilization of both the endoscope and the microscope allows the surgeon to benefit from the advantages of each modality.
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Clin Neurol Neurosurg · May 2014
Review Case ReportsSpontaneous regression of sequestrated lumbar disc herniations: Literature review.
Lumbar disc herniations (LDH) may regress with conservative management; however, this phenomenon is poorly understood for the sequestrated subtype of LDH. We present one of the first comprehensive literature reviews specifically addressing the spontaneous regression of sequestrated intervertebral discs. We reviewed all publications with lumbar disc herniations, sequestrated subtype. ⋯ Sequestrations may have the highest likelihood to radiographically regress in the shortest time frame in comparison to the remaining subtypes of LDH. The most likely mechanism for regression is an inflammatory response elicited against the free fragment. Patients with disc sequestrations may be managed conservatively, in the absence of intractable pain, inability to walk, weakness or symptoms suggestive of cauda equina syndrome.