The Journal of the American Dental Association
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Meta Analysis Comparative Study
The pulpal anesthetic efficacy of articaine versus lidocaine in dentistry: a meta-analysis.
The authors evaluated published evidence from controlled clinical trials regarding the efficacy of two local anesthetic solutions in providing successful pulpal anesthesia. ⋯ Research evidence supports using articaine versus lidocaine for achieving pulpal anesthesia when the infiltration mode of administration is used. It is premature to recommend articaine for mandibular block anesthesia in cases involving irreversible pulpitis.