The Journal of the American Dental Association
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Randomized Controlled Trial Comparative Study
Multivitamin therapy for recurrent aphthous stomatitis: a randomized, double-masked, placebo-controlled trial.
Recurrent aphthous stomatitis (RAS) is a painful condition of unknown etiology, affecting more than 2.5 billion people worldwide. Vitamin deficiencies have been implicated as a possible cause. ⋯ Clinicians should not recommend multi-vitamin supplementation routinely as prophylaxis for RAS.