Journal of the American Geriatrics Society
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Randomized Controlled Trial Multicenter Study Clinical Trial
Rapid emergency department intervention for older people reduces risk of functional decline: results of a multicenter randomized trial.
To determine the effectiveness of a two-stage (screening and nursing assessment) intervention for older patients in the emergency department (ED) who are at increased risk of functional decline and other adverse outcomes. ⋯ A two-stage ED intervention, consisting of screening with the ISAR tool followed by a brief, standardized nursing assessment and referral to primary and home care services, significantly reduced the rate of subsequent functional decline.
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Multicenter Study
The impact of insomnia on cognitive functioning in older adults.
To examine whether self-reported symptoms of insomnia independently increase risk of cognitive decline in older adults. ⋯ Chronic insomnia independently predicts incident cognitive decline in older men. More sensitive measures of cognitive performance may identify more subtle declines and may confirm whether insomnia is associated with cognitive decline in women.
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Randomized Controlled Trial Multicenter Study Clinical Trial
A randomized trial of exercise programs among older individuals living in two long-term care facilities: the FallsFREE program.
To use two different exercise programs over a 2-year period to reduce falls and their sequelae among residents of two long-term care facilities. ⋯ There were no significant differences in falls among the two exercise groups and the control group. Lack of treatment differences and low adherence rates suggest that residents of long-term care facilities may require individualized exercise interventions that can be adapted to their changing needs.
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Randomized Controlled Trial Multicenter Study Clinical Trial
Exercise rehabilitation improves functional outcomes and peripheral circulation in patients with intermittent claudication: a randomized controlled trial.
To determine the effects of a 6-month exercise program on ambulatory function, free-living daily physical activity, peripheral circulation, and health-related quality of life (QOL) in disabled older patients with intermittent claudication. ⋯ Improvements in claudication following exercise rehabilitation in older PAOD patients are dependent on improvements in peripheral circulation and walking economy. Improvement in treadmill claudication distances in these patients translated into increased accelerometer-derived physical activity in the community, which enabled the patients to become more functionally independent.
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Randomized Controlled Trial Multicenter Study Clinical Trial
The effect of aging on circulating levels of proinflammatory cytokines during septic shock. Norasept II Study Investigators.
As the proportion of the population that is older continues to rise, infection in older people has become an important healthcare problem. Although aging is associated with multiple abnormalities in immune function, the effect of aging on the production of proinflammatory cytokines has not been well studied under conditions of clinical stress. ⋯ Contrary to our expectations, we found that aging was not associated with a decline in the circulating levels of proinflammatory cytokines.