Journal of the American Veterinary Medical Association
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J. Am. Vet. Med. Assoc.
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J. Am. Vet. Med. Assoc. · Oct 2007
ReviewUse of bone morphogenetic proteins for augmentation of bone regeneration.
A large body of preclinical and clinical data now documents that recombinant BMPs can be used for skeletal regeneration in humans and animals. Recombinant human BMP-2 and BMP-7 have been approved for use in human patients with long-bone fractures and nonunions and in patients undergoing lumbar fusion or various maxillofacial and dental regenerative procedures. These products have also been made available for veterinary use.