Journal of the National Cancer Institute
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J. Natl. Cancer Inst. · Nov 2012
Randomized Controlled TrialIntegrated analysis of molecular and clinical prognostic factors in stage II/III colon cancer.
The prognostic potential of individual clinical and molecular parameters in stage II/III colon cancer has been investigated, but a thorough multivariable assessment of their relative impact is missing. ⋯ Concomitant assessment of molecular and clinical markers in multivariable analysis is essential to confirm or refute their independent prognostic value. Including molecular markers with independent prognostic value might allow more accurate prediction of prognosis than TNM staging alone.