Journal of neurosurgery
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Journal of neurosurgery · Aug 2003
Randomized Controlled Trial Clinical TrialEfficacy of aprotinin in children undergoing craniofacial surgery.
This prospective, randomized, placebo-controlled, double-blind trial was undertaken to assess the efficacy of aprotinin in reducing the need for blood transfusions in 39 children undergoing reconstructive craniofacial surgery. ⋯ Aprotinin decreased blood transfusion requirements in pediatric patients undergoing craniofacial reconstruction, thereby reducing the risks associated with exposure to banked blood components.