Journal of neurosurgery
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Journal of neurosurgery · Jan 2005
Gamma knife surgery for trigeminal neuralgia: improved initial response with two isocenters and increasing dose.
The authors sought to evaluate the initial response of trigeminal neuralgia (TN) to gamma knife surgery (GKS) based on the number of shots delivered and radiation dose. ⋯ Gamma knife surgery is an effective therapy for TN. Initial response rates appear to correlate with the number of shots and dose.
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Journal of neurosurgery · Jan 2005
Case ReportsGamma knife surgery for choroidal neovascularization in age-related macular degeneration. Technical note.
The authors conducted a study to determine a way of overcoming the poor-quality demonstration of choroidal neovascularization (CNV) associated with age-related macular degeneration (AMD) on conventional magnetic resonance (MR) imaging studies. The poor MR imaging demonstration of CNV in patients with AMD makes the use of gamma knife surgery more difficult. This difficulty, however, can be overcome by use of a modified time-of-flight MR imaging,sequence with Gd enhancement and coronal reconstruction.
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The authors sought to evaluate local tumor control, complications, and progression-free survival in patients harboring low-grade gliomas who were treated with Leksell gamma knife surgery (GKS). ⋯ Relatively high local tumor control with minimal complications was achieved.
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Journal of neurosurgery · Jan 2005
Microsurgical anatomy of cerebral revascularization. Part II: posterior circulation.
Revascularization is an important component of treatment for complex aneurysms, skull base tumors, and vertebrobasilar ischemia in the posterior circulation. In this study, the authors examined the microsurgical anatomy related to cerebral revascularization in the posterior circulation and demonstrate various procedures for bypass surgery. ⋯ Although a clear guideline for cerebral revascularization procedures has not yet been established, it is important to understand various microsurgical techniques and their related anatomical structures. This will help surgeons consider surgical indications for treatment of patients with vertebrobasilar ischemia caused by aneurysms, tumors, or atherosclerotic diseases in the posterior circulation.
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Journal of neurosurgery · Jan 2005
Computational model for the estimation of the extracranial doses received during Leksell gamma knife model C treatment.
Extracranial doses received by patients undergoing Leksell gamma knife surgery (GKS) can be of clinical concern. Therefore, the ability to preestimate peripheral doses received outside the treatment field during the GKS would be beneficial and could be used for the optimization of treatment planning by providing a reference for practitioners to calculate the extracranial dose burden to the body before the start of treatment. ⋯ The peripheral dose depended on the collimator size with a logarithmic dependence on collimator size and a linear dependence on the number of shots. This model can be used for the estimation of peripheral doses with a total error less than 20%. This information can help clinicians with treatment planning optimization, especially in patients with long survival expectancy.