Journal of neurosurgery
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Journal of neurosurgery · Jan 2005
Gamma knife thalamotomy for movement disorders: evaluation of the thalamic lesion and clinical results.
The authors studied the effects of gamma knife thalamotomy (GKT) on Parkinson disease-related tremor and essential tremor before and after reloading of radioactive cobalt. ⋯ The shorter delay in clinical improvement and smaller lesion size may be related to an increased radiation dose.
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Journal of neurosurgery · Jan 2005
Case ReportsGamma knife surgery for refractory postherpetic trigeminal neuralgia: targeting in one session both the retrogasserian trigeminal nerve and the centromedian nucleus of the thalamus.
The authors tested the hypothesis that two targets are needed to treat postherpetic trigeminal neuralgia (TN): one in the trigeminal nerve for the direct sharp pain and one in the thalamus for the diffuse burning pain. ⋯ Combined GKS of the centromedian nucleus and trigeminal nerve in a single treatment session is feasible and safe, and the effect was promising. A larger study is required to confirm and expand these results.
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Journal of neurosurgery · Jan 2005
Microsurgical anatomy of cerebral revascularization. Part I: anterior circulation.
Revascularization is an important component of treatment for complex aneurysms that require parent vessel occlusion, skull base tumors that involve major vessels, and certain ischemic diseases. In this study, the authors examined the microsurgical anatomy of cerebral revascularization in the anterior circulation by demonstrating various procedures for bypass surgery. ⋯ It is important to understand the methods of bypass procedures and to consider indications in which cerebral revascularization is needed.
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Journal of neurosurgery · Jan 2005
Radiosurgery of vestibular schwannomas: summary of experience in 829 cases.
Management options for vestibular schwannomas (VSs) have greatly expanded since the introduction of stereotactic radiosurgery. Optimal outcomes reflect long-term tumor control, preservation of cranial nerve function, and retention of quality of life. The authors review their 15-year experience. ⋯ Superior imaging, multiple isocenter volumetric conformal dose planning, and optimal precision and dose delivery contributed to the long-term success of GKS, including in those patients in whom initial microsurgery had failed. Gamma knife surgery provides a low risk, minimally invasive treatment option for patients with newly diagnosed or residual VS. Cranial nerve preservation and quality of life maintenance are possible in long-term follow up.
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Journal of neurosurgery · Jan 2005
Influence of endothelial nitric oxide synthase T-786C single nucleotide polymorphism on aneurysm size.
Among patients with aneurysms, those with heterozygous (T/C) endothelial nitric oxide synthase (eNOS) T-786C single nucleotide polymorphism (SNP), a mutation reducing endothelial nitric oxide synthesis, are reported to have larger ruptured intracranial aneurysms (IAs) than those with homozygous (C/C or T/T) genotype. The authors tested patients harboring aneurysms for eNOS T-786C SNP in two populations--Japanese and Korean. ⋯ The eNOS T-786C SNP genotype does not influence the size of aneurysms.