Journal of neurosurgery
-
Journal of neurosurgery · Jan 2005
Case ReportsLong-term results of gamma knife surgery for growth hormone-producing pituitary adenoma: is the disease difficult to cure?
The authors conducted a study to determine the long-term results of gamma knife surgery for residual or recurrent growth hormine (GH)-producing pituitary adenomas and to compare the results with those after treatment of other pituitary adenomas. ⋯ Gamma knife surgery was effective and safe for the control of tumors; however, normalization of GH and IGF-1 secretion was difficult to achieve in cases with large tumors and low-dose radiation. Gamma knife radiosurgery is thus indicated for small tumors after surgery or medication therapy when a relatively high-dose radiation is required.
-
Journal of neurosurgery · Jan 2005
Analysis of long-term outcomes and prognostic factors in patients with non-small cell lung cancer brain metastases treated by gamma knife radiosurgery.
The authors conducted a study to evaluate the long-term outcomes and prognostic factors for survival in a large series of patients treated by gamma knife surgery (GKS) for non-small cell lung cancer (NSCLC) brain metastases. ⋯ Gamma knife surgery is a useful treatment for brain metastases from NSCLC.
-
Journal of neurosurgery · Jan 2005
Postoperative cerebral hyperperfusion associated with impaired cognitive function in patients undergoing carotid endarterectomy.
Cognitive impairment occurs in 20 to 30% of patients following carotid endarterectomy (CEA). The purpose of the present study was to determine whether postoperative cerebral hyperperfusion is associated with impairment of cognitive function in patients undergoing that procedure. ⋯ Postoperative cerebral hyperperfusion is associated with impairment of cognitive function in patients undergoing CEA. Furthermore, the development of hyperperfusion syndrome is associated with the persistence of postoperative cognitive impairment.
-
Journal of neurosurgery · Jan 2005
Long-term results of Leksell gamma knife surgery for trigeminal schwannomas.
The authors evaluated the long-term efficacy of gamma knife surgery (GKS) in patients with trigeminal schwannomas. ⋯ Radiosurgery proved to be an effective treatment for small- and medium-sized trigeminal schwannomas. Some larger tumors are also suitable for radiosurgery if there is no significant brainstem compression.
-
Journal of neurosurgery · Jan 2005
Prolonged survival in a subgroup of patients with brain metastases treated by gamma knife surgery.
The authors analyzed the factors involved in determining prolonged survival (> or = 24 months) in patients with brain metastases treated by gamma knife surgery (GKS). ⋯ Aggressive local therapy with GKS, repeated GKS, and GKS plus surgery can achieve increased survival in a subgroup of patients with stable primary disease, no third-organ involvement, and long primary-brain secondary intervals.