Journal of neurosurgery
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Journal of neurosurgery · Jan 2005
A simple method for predicting imaging-based complications following gamma knife surgery for cerebral arteriovenous malformations.
The authors studied the relationship between dose planning parameters and complications in the treatment of cerebral arteriovenous malformations (AVMs). ⋯ The integral dose could be used as a guideline for the prescription dose. Arguments are made for maximizing the prescription dose for the long-term safety of the patient.
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The authors analyzed tumor control rates and complications in patients with superficially located meningiomas after gamma knife surgery (GKS). ⋯ There was a good tumor control rate with a high complication rate. Longer follow up of more patients is needed. Adjusting the dose-volume relationship should be considered to reduce complications.
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Journal of neurosurgery · Jan 2005
The long-term results of gamma knife radiosurgery for hemangioblastomas of the brain.
The authors assessed the long-term result of gamma knife surgery (GKS) for hemangioblastomas of the brain (HABs) and show histopathological findings after GKS. ⋯ Gamma knife surgery was a useful choice for small- or medium-sized, solid HAB in the long term, especially when the tumor margin dose was 18 Gy. Although GKS can treat multiple tumors in a single session, for HABs associated with VHL disease, GKS faces the dual problems of tumor recurrence or development of a new tumor.
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The purpose of this study was to assess the benefits of radiosurgery for cavernous hemangioma. ⋯ The authors found that GKS was an effective treatment modality for cavernous hemangiomas, especially for those located within the brainstem, basal ganglia, or deep portions of the brain. It can reduce seizure frequency significantly although this takes time. In the group receiving a marginal dose below 15 Gy the patients fared better than when the dose exceeded 15 Gy.
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The authors conducted a study to evaluate the safety and efficacy of gamma knife surgery (GKS) for the treatment of brain metastases from lung cancer. ⋯ The risk-benefit ratio of GKS in this series was satisfactory. There was no difference in response rates of the two tumor types, and WBRT did not improve the duration of survival.