Journal of neurosurgery
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Journal of neurosurgery · Nov 2007
Randomized Controlled TrialProspective randomized double-blind trial of bilateral thalamic deep brain stimulation in adults with Tourette syndrome.
The severity of Tourette syndrome (TS) typically peaks just before adolescence and diminishes afterward. In some patients, however, TS progresses into adulthood, and proves to be medically refractory. The authors conducted a prospective double-blind crossover trial of bilateral thalamic deep brain stimulation (DBS) in five adults with TS. ⋯ Bilateral thalamic DBS appears to reduce tic frequency and severity in some patients with TS who have exhausted other available means of treatment.