Journal of neurosurgery
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Journal of neurosurgery · Dec 2010
Randomized Controlled Trial Clinical TrialA closer look at unilateral versus bilateral deep brain stimulation: results of the National Institutes of Health COMPARE cohort.
In this paper, the authors' aim was to examine reasons underpinning decisions to undergo, or alternatively forgo, a second-sided deep brain stimulation (DBS) implantation in patients with Parkinson disease (PD). ⋯ Unilateral DBS is an effective treatment for a subset of patients with PD. Baseline asymmetry is an important factor in the effectiveness and decision-making process between unilateral and bilateral DBS. Patients with GPi DBS in this cohort were more likely to choose to remain with unilateral implantation.