Journal of neurosurgery
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Journal of neurosurgery · Feb 2016
Randomized Controlled TrialA double-blind randomized trial on the clinical effect of different shunt valve settings in idiopathic normal pressure hydrocephalus.
The study aim was to examine the effect of gradually reducing the opening pressure on symptoms and signs in the shunt treatment of idiopathic normal pressure hydrocephalus (iNPH). ⋯ Gradual reduction of the valve setting from 20 to 4 cm H2O did not improve outcome compared with a fixed valve setting of 12 cm H2O. Improvement after shunt surgery in iNPH patients was evident within 3 months, irrespective of valve setting.