Journal of endodontics
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Journal of endodontics · May 2013
Randomized Controlled Trial Comparative StudyA prospective, randomized, double-blind comparison of the injection pain and anesthetic onset of 2% lidocaine with 1:100,000 epinephrine buffered with 5% and 10% sodium bicarbonate in maxillary infiltrations.
Local anesthetics can be buffered to a physiological pH before injection to decrease the time of onset and reduce injection pain. ⋯ Two percent lidocaine with 1:100,000 epinephrine buffered with 5% or 10% sodium bicarbonate did not differ from nonbuffered solutions in anesthetic onset or injection pain in maxillary infiltrations of canines with healthy pulps.