European urology
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Randomized Controlled Trial Clinical Trial
Adjuvant hormonal treatment with radiotherapy for locally advanced prostate cancer.
Long-term results of radiotherapy in locally advanced prostate cancer are poor due to local and distant failures. Since prostate cancer is hormone dependent, tumor androgen deprivation may enhance tumor eradication. ⋯ Androgen suppression prior to and during radiation improves disease-free survival; adjuvant hormonal therapy with an LH-RHa during and after radiation improves overall survival.