European urology
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Randomized Controlled Trial Multicenter Study
Screening for prostate cancer: results of the Rotterdam section of the European randomized study of screening for prostate cancer.
Evidence from randomized trials on the effects of screening for prostate cancer (PCa) on disease-specific mortality accumulates slowly with increasing follow-up. ⋯ Systematic PSA-based screening reduced PCa-specific mortality by 32% in the age range of 55-69 yr. The roughly twofold higher incidence in the S-arm underlines the importance of tools to better identify those men who would benefit from screening.