British dental journal
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British dental journal · Feb 2003
Randomized Controlled Trial Comparative Study Clinical TrialAn investigation into the comparative efficacy of soluble aspirin and solid paracetamol in postoperative pain after third molar surgery.
To compare the efficacy of soluble aspirin 900 mg and paracetamol 1,000 mg in patients with postoperative pain after third molar surgery. ⋯ The findings from this study showed that soluble aspirin 900 mg provides significant and more rapid analgesia than paracetamol 1,000 mg in the early postoperative period after third molar surgery.
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British dental journal · Apr 2002
Randomized Controlled Trial Comparative Study Clinical TrialA study of the effectiveness of oral midazolam sedation for orthodontic extraction of permanent teeth in children: a prospective, randomised, controlled, crossover trial.
To assess the safety, effectiveness and acceptability of o:ral midazolam sedation for orthodontic extraction of permanent teeth in children. ⋯ Oral midazolam (0.5mg/kg) appears to be a safe and acceptable form of sedation for 10-16 year old paediatric dental patients.
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British dental journal · Mar 2002
Randomized Controlled Trial Clinical TrialA randomised crossover trial of post-operative cognitive and psychomotor recovery from benzodiazepine sedation: effects of reversal with flumazenil over a prolonged recovery period.
To study the post-operative cognitive and psychomotor recovery from midazolam conscious sedation, after reversal with the benzodiazepine antagonist flumazenil over a prolonged recovery period. ⋯ The cognitive and psychomotor effects of the sedation were not fully reversed by flumazenil. Cognitive impairments were still present up to 6 hours post-reversal, despite patients appearing clinically more alert. This has important implications for treatment protocols and discharge instructions.
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British dental journal · Sep 2001
Randomized Controlled Trial Multicenter Study Clinical TrialPain control with paracetamol from a sustained release formulation and a standard release formulation after third molar surgery: a randomised controlled trial.
To compare the analgesic efficacy and safety of a sustained release (SR) paracetamol formulation (Panadol Extend) with a standard immediate release (IR) formulation (Panadol) after third molar surgery. ⋯ SR paracetamol and IR paracetamol are clinically and statistically equivalent. While SR paracetamol and IR paracetamol were similar in terms of both onset of analgesia and peak analgesic effect, SR paracetamol had a longer duration of activity than IR paracetamol. The safety profiles of SR paracetamol and IR paracetamol were found to be very similar.
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British dental journal · May 2001
Randomized Controlled Trial Clinical TrialThe influence of two different dental local anaesthetic solutions on the haemodynamic responses of children undergoing restorative dentistry: a randomised, single-blind, split-mouth study.
This investigation was designed to study the haemodynamic effects of two different local anaesthetic solutions during restorative dental treatment in children. ⋯ The choice of local anaesthetic solution influences the haemodynamic response during restorative treatment in children.