The Journal of antimicrobial chemotherapy
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J. Antimicrob. Chemother. · Feb 2008
Multicenter Study Comparative StudyColistin and rifampicin in the treatment of multidrug-resistant Acinetobacter baumannii infections.
The increased incidence of nosocomial infections by multidrug-resistant organisms has motivated the re-introduction of colistin in combination with other antimicrobials in the treatment of infections. We describe the clinical and microbiological outcomes of patients infected with multidrug-resistant Acinetobacter baumannii who were treated with a combination of colistin and rifampicin. ⋯ Colistin and rifampicin appears to be an effective and safe combination therapy for severe infections due to multidrug-resistant A. baumannii.