The Journal of antimicrobial chemotherapy
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J. Antimicrob. Chemother. · Apr 2013
Multicenter Study Comparative StudyFluconazole versus an echinocandin for Candida glabrata fungaemia: a retrospective cohort study.
We studied whether fluconazole or echinocandin treatment of Candida glabrata fungaemia results in superior outcomes. ⋯ Severity of illness and choice of antifungal predict response in patients with C. glabrata fungaemia. Antifungal choice, however, does not influence mortality. In addition, new CLSI C. glabrata fluconazole susceptibility breakpoints are predictive of response when fluconazole is dosed appropriately.